Exploiting the Chiral Ligands of Bis(imidazolinyl)- and Bis(oxazolinyl)thiophenes—Synthesis and Application in Cu-Catalyzed Friedel–Crafts Asymmetric Alkylation

Five new C(2)-symmetric chiral ligands of 2,5-bis(imidazolinyl)thiophene (L1–L3) and 2,5-bis(oxazolinyl)thiophene (L4 and L5) were synthesized from thiophene-2,5-dicarboxylic acid (1) with enantiopure amino alcohols (4a–c) in excellent optical purity and chemical yield. The utility of these new chir...

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Detalles Bibliográficos
Autores principales: Islam, Mohammad Shahidul, Alammari, Abdullah Saleh, Barakat, Assem, Alshahrani, Saeed, Haukka, Matti, Al-Majid, Abdullah Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658940/
https://www.ncbi.nlm.nih.gov/pubmed/34885989
http://dx.doi.org/10.3390/molecules26237408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658940/
https://www.ncbi.nlm.nih.gov/pubmed/34885989
http://dx.doi.org/10.3390/molecules26237408

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