Synthesis and Biological Studies on (KLAKLAK)(2)-NH(2) Analog Containing Unnatural Amino Acid β-Ala and Conjugates with Second Pharmacophore

(1) Background: Peptides are good candidates for anticancer drugs due to their natural existence in the body and lack of secondary effects. (KLAKLAK)(2) is an antimicrobial peptide that also shows good anticancer properties. (2) Methods: The Solid Phase Peptide Synthesis (Fmoc-strategy) was used for...

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Detalles Bibliográficos
Autores principales: Jaber, Sirine, Nemska, Veronica, Iliev, Ivan, Ivanova, Elena, Foteva, Tsvetelina, Georgieva, Nelly, Givechev, Ivan, Naydenova, Emilia, Karadjova, Veronika, Danalev, Dancho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658989/
https://www.ncbi.nlm.nih.gov/pubmed/34885902
http://dx.doi.org/10.3390/molecules26237321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658989/
https://www.ncbi.nlm.nih.gov/pubmed/34885902
http://dx.doi.org/10.3390/molecules26237321

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