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Synthesis and Biological Studies on (KLAKLAK)(2)-NH(2) Analog Containing Unnatural Amino Acid β-Ala and Conjugates with Second Pharmacophore
(1) Background: Peptides are good candidates for anticancer drugs due to their natural existence in the body and lack of secondary effects. (KLAKLAK)(2) is an antimicrobial peptide that also shows good anticancer properties. (2) Methods: The Solid Phase Peptide Synthesis (Fmoc-strategy) was used for...
Autores principales: | Jaber, Sirine, Nemska, Veronica, Iliev, Ivan, Ivanova, Elena, Foteva, Tsvetelina, Georgieva, Nelly, Givechev, Ivan, Naydenova, Emilia, Karadjova, Veronika, Danalev, Dancho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658989/ https://www.ncbi.nlm.nih.gov/pubmed/34885902 http://dx.doi.org/10.3390/molecules26237321 |
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