Expression, Purification and Characterization of a Novel Hybrid Peptide CLP with Excellent Antibacterial Activity

CLP is a novel hybrid peptide derived from CM4, LL37 and TP5, with significantly reduced hemolytic activity and increased antibacterial activity than parental antimicrobial peptides. To avoid host toxicity and obtain high-level bio-production of CLP, we established a His-tagged SUMO fusion expressio...

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Detalles Bibliográficos
Autores principales: Cheng, Junhao, Ahmat, Marhaba, Guo, Henan, Wei, Xubiao, Zhang, Lulu, Cheng, Qiang, Zhang, Jing, Wang, Junyong, Si, Dayong, Zhang, Yueping, Zhang, Rijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659006/
https://www.ncbi.nlm.nih.gov/pubmed/34885732
http://dx.doi.org/10.3390/molecules26237142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659006/
https://www.ncbi.nlm.nih.gov/pubmed/34885732
http://dx.doi.org/10.3390/molecules26237142

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