A Review of HER4 (ErbB4) Kinase, Its Impact on Cancer, and Its Inhibitors

HER4 is a receptor tyrosine kinase that is required for the evolution of normal body systems such as cardiovascular, nervous, and endocrine systems, especially the mammary glands. It is activated through ligand binding and activates MAPKs and PI3K/AKT pathways. HER4 is commonly expressed in many hum...

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Detalles Bibliográficos
Autores principales: El-Gamal, Mohammed I., Mewafi, Nada H., Abdelmotteleb, Nada E., Emara, Minnatullah A., Tarazi, Hamadeh, Sbenati, Rawan M., Madkour, Moustafa M., Zaraei, Seyed-Omar, Shahin, Afnan I., Anbar, Hanan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659013/
https://www.ncbi.nlm.nih.gov/pubmed/34885957
http://dx.doi.org/10.3390/molecules26237376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659013/
https://www.ncbi.nlm.nih.gov/pubmed/34885957
http://dx.doi.org/10.3390/molecules26237376

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