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A Review of HER4 (ErbB4) Kinase, Its Impact on Cancer, and Its Inhibitors
HER4 is a receptor tyrosine kinase that is required for the evolution of normal body systems such as cardiovascular, nervous, and endocrine systems, especially the mammary glands. It is activated through ligand binding and activates MAPKs and PI3K/AKT pathways. HER4 is commonly expressed in many hum...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659013/ https://www.ncbi.nlm.nih.gov/pubmed/34885957 http://dx.doi.org/10.3390/molecules26237376 |