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Design of a High-Sensitivity Dimeric G-Quadruplex/Hemin DNAzyme Biosensor for Norovirus Detection

G-quadruplexes can bind with hemin to form peroxidase-like DNAzymes that are widely used in the design of biosensors. However, the catalytic activity of G-quadruplex/hemin DNAzyme is relatively low compared with natural peroxidase, which hampers its sensitivity and, thus, its application in the dete...

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Detalles Bibliográficos
Autores principales: Zhang, Yun, Ma, Xinao, Zhang, Jingtian, Luo, Feixian, Wang, Wenshu, Cui, Xiaojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659037/
https://www.ncbi.nlm.nih.gov/pubmed/34885931
http://dx.doi.org/10.3390/molecules26237352