Synthesis, Identification, Computer-Aided Docking Studies, and ADMET Prediction of Novel Benzimidazo-1,2,3-triazole Based Molecules as Potential Antimicrobial Agents

2-azido-1H-benzo[d]imidazole derivatives 1a,b were reacted with a β-ketoester such as acetylacetone in the presence of sodium ethoxide to obtain the desired molecules 2a,b. The latter acted as a key molecule for the synthesis of new carbazone derivatives 4a,b that were submitted to react with 2-oxo-...

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Detalles Bibliográficos
Autores principales: Rashdan, Huda R. M., Abdelmonsef, Aboubakr H., Abou-Krisha, Mortaga M., Yousef, Tarek A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659132/
https://www.ncbi.nlm.nih.gov/pubmed/34885701
http://dx.doi.org/10.3390/molecules26237119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659132/
https://www.ncbi.nlm.nih.gov/pubmed/34885701
http://dx.doi.org/10.3390/molecules26237119

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