Computational Simulation of HIV Protease Inhibitors to the Main Protease (Mpro) of SARS-CoV-2: Implications for COVID-19 Drugs Design

SARS-CoV-2 is highly homologous to SARS-CoV. To date, the main protease (Mpro) of SARS-CoV-2 is regarded as an important drug target for the treatment of Coronavirus Disease 2019 (COVID-19). Some experiments confirmed that several HIV protease inhibitors present the inhibitory effects on the replica...

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Detalles Bibliográficos
Autores principales: Yu, Wei, Wu, Xiaomin, Zhao, Yizhen, Chen, Chun, Yang, Zhiwei, Zhang, Xiaochun, Ren, Jiayi, Wang, Yueming, Wu, Changwen, Li, Chengming, Chen, Rongfeng, Wang, Xiaoli, Zheng, Weihong, Liao, Huaxin, Yuan, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659229/
https://www.ncbi.nlm.nih.gov/pubmed/34885967
http://dx.doi.org/10.3390/molecules26237385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659229/
https://www.ncbi.nlm.nih.gov/pubmed/34885967
http://dx.doi.org/10.3390/molecules26237385

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