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Taurochenodeoxycholic Acid Increases cAMP Content via Specially Interacting with Bile Acid Receptor TGR5

Taurochenodeoxycholic acid (TCDCA) is one of the main components of bile acids (BAs). TCDCA has been reported as a signaling molecule, exerting anti-inflammatory and immunomodulatory functions. However, it is not well known whether those effects are mediated by TGR5. This study aimed to elucidate th...

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Detalles Bibliográficos
Autores principales: Qi, Youchao, Shi, Linkai, Duan, Guozhen, Ma, Yonggui, Li, Peifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659238/
https://www.ncbi.nlm.nih.gov/pubmed/34885648
http://dx.doi.org/10.3390/molecules26237066