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Continuous Flow Synthesis of Propofol

Herein, we report a continuous flow process for the synthesis of 2,6-diisopropylphenol—also known as Propofol—a short-acting intravenous anesthesia, widely used in intensive care medicine to provide sedation and hypnosis. The synthesis is based on a two-step procedure: a double Friedel–Crafts alkyla...

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Detalles Bibliográficos
Autores principales: Mougeot, Romain, Jubault, Philippe, Legros, Julien, Poisson, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659244/
https://www.ncbi.nlm.nih.gov/pubmed/34885756
http://dx.doi.org/10.3390/molecules26237183