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Continuous Flow Synthesis of Propofol
Herein, we report a continuous flow process for the synthesis of 2,6-diisopropylphenol—also known as Propofol—a short-acting intravenous anesthesia, widely used in intensive care medicine to provide sedation and hypnosis. The synthesis is based on a two-step procedure: a double Friedel–Crafts alkyla...
Autores principales: | Mougeot, Romain, Jubault, Philippe, Legros, Julien, Poisson, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659244/ https://www.ncbi.nlm.nih.gov/pubmed/34885756 http://dx.doi.org/10.3390/molecules26237183 |
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