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Antibacterial Polymers Based on Poly(2-hydroxyethyl methacrylate) and Thiazolium Groups with Hydrolytically Labile Linkages Leading to Inactive and Low Cytotoxic Compounds

Herein, we develop a well-defined antibacterial polymer based on poly(2-hydroxyethyl methacrylate) (PHEMA) and a derivative of vitamin B1, easily degradable into inactive and biocompatible compounds. Hence, thiazole moiety was attached to HEMA monomer through a carbonate pH-sensitive linkage and the...

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Detalles Bibliográficos
Autores principales: Cuervo-Rodríguez, Rocío, López-Fabal, Fátima, Muñoz-Bonilla, Alexandra, Fernández-García, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659269/
https://www.ncbi.nlm.nih.gov/pubmed/34885630
http://dx.doi.org/10.3390/ma14237477