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The Polyphenols α-Mangostin and Nordihydroguaiaretic Acid Induce Oxidative Stress, Cell Cycle Arrest, and Apoptosis in a Cellular Model of Medulloblastoma

Medulloblastoma is a common malignant brain tumor in the pediatric age. The current therapeutics present serious collateral effects. Polyphenols α-mangostin and nordihydroguaiaretic acid (NDGA) exert potent antitumoral activity in different cancer models, although their antitumoral effects have not...

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Detalles Bibliográficos
Autores principales: Rojas-Ochoa, Alberto, Córdova, Emilio J., Carrillo-García, Adela, Lizano, Marcela, Pedraza-Chaverri, José, Patiño, Nelly, Cruz-Gregorio, Alfredo, Osnaya, Norma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659270/
https://www.ncbi.nlm.nih.gov/pubmed/34885809
http://dx.doi.org/10.3390/molecules26237230