Identification of a Novel Delta Opioid Receptor Agonist Chemotype with Potential Negative Allosteric Modulator Capabilities

The δ-opioid receptor (δOR) holds great potential as a therapeutic target. Yet, clinical drug development, which has focused on δOR agonists that mimic the potent and selective tool compound SNC80 have largely failed. It has increasingly become apparent that the SNC80 scaffold carries with it potent...

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Detalles Bibliográficos
Autores principales: Meqbil, Yazan J., Su, Hongyu, Cassell, Robert J., Mores, Kendall L., Gutridge, Anna M., Cummins, Benjamin R., Chen, Lan, van Rijn, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659279/
https://www.ncbi.nlm.nih.gov/pubmed/34885825
http://dx.doi.org/10.3390/molecules26237236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659279/
https://www.ncbi.nlm.nih.gov/pubmed/34885825
http://dx.doi.org/10.3390/molecules26237236

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