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The good, the bad, and the ugly: Evolutionary and pathological aspects of gene dosage alterations
Diploid organisms contain a maternal and a paternal genome complement that is thought to provide robustness and allow developmental progression despite genetic perturbations that occur in heterozygosity. However, changes affecting gene dosage from the chromosome down to the individual gene level pos...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659298/ https://www.ncbi.nlm.nih.gov/pubmed/34882671 http://dx.doi.org/10.1371/journal.pgen.1009906 |