An aromatic imidazoline derived from chloroquinoline triggers cell cycle arrest and inhibits with high selectivity the Trypanosoma cruzi mammalian host-cells infection

Trypanosoma cruzi is a hemoflagellated parasite causing Chagas disease, which affects 6–8 million people in the Americas. More than one hundred years after the description of this disease, the available drugs for treating the T. cruzi infection remain largely unsatisfactory. Chloroquinoline and aryl...

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Detalles Bibliográficos
Autores principales: Cuevas-Hernández, Roberto I., Girard, Richard M. B. M., Krstulović, Luka, Bajić, Miroslav, Silber, Ariel Mariano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659321/
https://www.ncbi.nlm.nih.gov/pubmed/34843481
http://dx.doi.org/10.1371/journal.pntd.0009994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659321/
https://www.ncbi.nlm.nih.gov/pubmed/34843481
http://dx.doi.org/10.1371/journal.pntd.0009994

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