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Sequence and vector shapes vaccine induced antibody effector functions in HIV vaccine trials

Despite the advent of long-acting anti-retroviral therapy able to control and prevent infection, a preventative vaccine remains a global priority for the elimination of HIV. The moderately protective RV144 vaccine trial suggested functional IgG1 and IgG3 antibodies were a potential correlate of prot...

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Detalles Bibliográficos
Autores principales: Fischinger, Stephanie, Cizmeci, Deniz, Deng, Davy, Grant, Shannon P., Frahm, Nicole, McElrath, Julie, Fuchs, Jonathan, Bart, Pierre-Alexandre, Pantaleo, Giuseppe, Keefer, Michael, O. Hahn, William, Rouphael, Nadine, Churchyard, Gavin, Moodie, Zoe, Donastorg, Yeycy, Streeck, Hendrik, Alter, Galit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659322/
https://www.ncbi.nlm.nih.gov/pubmed/34843602
http://dx.doi.org/10.1371/journal.ppat.1010016