Topical Treatment of Human Skin and Cultured Keratinocytes with High-Dose Spironolactone Reduces XPB Expression and Induces Toxicity

Spironolactone (SP) is used to treat a variety of disparate disease states ranging from heart failure to acne through antagonism of the mineralocorticoid and androgen receptors. Although normally taken as an oral medication, recent studies have explored the topical application of SP onto the skin. H...

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Detalles Bibliográficos
Autores principales: Carpenter, M. Alexandra, Kemp, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659383/
https://www.ncbi.nlm.nih.gov/pubmed/34909723
http://dx.doi.org/10.1016/j.xjidi.2021.100023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659383/
https://www.ncbi.nlm.nih.gov/pubmed/34909723
http://dx.doi.org/10.1016/j.xjidi.2021.100023

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