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Characterization of Single Nucleotide Variants of OPN3 Gene in Melanocytic Nevi and Melanoma

In this study, we examined single nucleotide variants (SNVs) of the OPN3 gene in malignant melanoma and melanocytic nevi. A total of 20 variants of SNVs were detected. Of these variants, five nonsynonymous mutations of OPN3 were identified, including c.T152C, c.T401C, c.G547A, c.G768A, and c.G992A....

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Feng, Jianglong, Zeng, Wen, Zhou, Zhixu, Wang, Yu, Lu, Hongguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659391/
https://www.ncbi.nlm.nih.gov/pubmed/34909710
http://dx.doi.org/10.1016/j.xjidi.2021.100006