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Alphaherpesvirus-induced activation of plasmacytoid dendritic cells depends on the viral glycoprotein gD and is inhibited by non-infectious light particles

Plasmacytoid dendritic cells (pDC) are important innate immune cells during the onset of viral infections as they are specialized in the production of massive amounts of antiviral type I interferon (IFN). Alphaherpesviruses such as herpes simplex virus (HSV) or pseudorabies virus (PRV) are double st...

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Detalles Bibliográficos
Autores principales: Delva, Jonas L., Van Waesberghe, Cliff, Klupp, Barbara G., Mettenleiter, Thomas C., Favoreel, Herman W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659615/
https://www.ncbi.nlm.nih.gov/pubmed/34843605
http://dx.doi.org/10.1371/journal.ppat.1010117