Using a Machine Learning Approach to Identify Low-Frequency and Rare FLG Alleles Associated with Remission of Atopic Dermatitis

Atopic dermatitis (AD) is a common relapsing inflammatory skin disease. FLG is the gene most consistently associated with AD. Loss-of-function variants in FLG have been previously associated with AD. Low-frequency and rare alleles (minor allele frequency < 5%) in this gene have been given less at...

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Detalles Bibliográficos
Autores principales: Berna, Ronald, Mitra, Nandita, Hoffstad, Ole, Wubbenhorst, Bradley, Nathanson, Katherine L., Margolis, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659778/
https://www.ncbi.nlm.nih.gov/pubmed/34909743
http://dx.doi.org/10.1016/j.xjidi.2021.100046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659778/
https://www.ncbi.nlm.nih.gov/pubmed/34909743
http://dx.doi.org/10.1016/j.xjidi.2021.100046

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