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Clostridium butyricum Alleviates Enterotoxigenic Escherichia coli K88-Induced Oxidative Damage Through Regulating the p62-Keap1-Nrf2 Signaling Pathway and Remodeling the Cecal Microbial Community

Clostridium butyricum (CB) can enhance antioxidant capacity and alleviate oxidative damage, but the molecular mechanism by which this occurs remains unclear. This study used enterotoxigenic Escherichia coli (ETEC) K88 as a pathogenic model, and the p62-Keap1-Nrf2 signaling pathway and intestinal mic...

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Detalles Bibliográficos
Autores principales: Li, Haihua, Shang, Zhiyuan, Liu, Xuejiao, Qiao, Yingying, Wang, Kewei, Qiao, Jiayun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660075/
https://www.ncbi.nlm.nih.gov/pubmed/34899723
http://dx.doi.org/10.3389/fimmu.2021.771826