Narrow mutational signatures drive acquisition of multidrug resistance in the fungal pathogen Candida glabrata

Fungal infections are a growing medical concern, in part due to increased resistance to one or multiple antifungal drugs. However, the evolutionary processes underpinning the acquisition of antifungal drug resistance are poorly understood. Here, we used experimental microevolution to study the adapt...

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Detalles Bibliográficos
Autores principales: Ksiezopolska, Ewa, Schikora-Tamarit, Miquel Àngel, Beyer, Reinhard, Nunez-Rodriguez, Juan Carlos, Schüller, Christoph, Gabaldón, Toni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660101/
https://www.ncbi.nlm.nih.gov/pubmed/34699784
http://dx.doi.org/10.1016/j.cub.2021.09.084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660101/
https://www.ncbi.nlm.nih.gov/pubmed/34699784
http://dx.doi.org/10.1016/j.cub.2021.09.084

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