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Narrow mutational signatures drive acquisition of multidrug resistance in the fungal pathogen Candida glabrata
Fungal infections are a growing medical concern, in part due to increased resistance to one or multiple antifungal drugs. However, the evolutionary processes underpinning the acquisition of antifungal drug resistance are poorly understood. Here, we used experimental microevolution to study the adapt...
Autores principales: | Ksiezopolska, Ewa, Schikora-Tamarit, Miquel Àngel, Beyer, Reinhard, Nunez-Rodriguez, Juan Carlos, Schüller, Christoph, Gabaldón, Toni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660101/ https://www.ncbi.nlm.nih.gov/pubmed/34699784 http://dx.doi.org/10.1016/j.cub.2021.09.084 |
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