The role of nanoparticle format and route of administration on self-amplifying mRNA vaccine potency

The efficacy of RNA-based vaccines has been recently demonstrated, leading to the use of mRNA-based COVID-19 vaccines. The application of self-amplifying mRNA within these formulations may offer further enhancement to these vaccines, as self-amplifying mRNA replicons enable longer expression kinetic...

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Detalles Bibliográficos
Autores principales: Anderluzzi, Giulia, Lou, Gustavo, Woods, Stuart, Schmidt, Signe Tandrup, Gallorini, Simona, Brazzoli, Michela, Johnson, Russell, Roberts, Craig W., O'Hagan, Derek T., Baudner, Barbara C., Perrie, Yvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660137/
https://www.ncbi.nlm.nih.gov/pubmed/34896446
http://dx.doi.org/10.1016/j.jconrel.2021.12.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660137/
https://www.ncbi.nlm.nih.gov/pubmed/34896446
http://dx.doi.org/10.1016/j.jconrel.2021.12.008

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