Cystic Fibrosis: Systems Biology Analysis from Homozygous p.Phe508del Variant Patients' Samples Reveals Perturbations in Tissue-Specific Pathways

Cystic fibrosis (CF) is an autosomal recessive disorder, caused by diverse genetic variants for the CF transmembrane conductance regulator (CFTR) protein. Among these, p.Phe508del is the most prevalent variant. The effects of this variant on the physiology of each tissue remains unknown. This study...

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Detalles Bibliográficos
Autores principales: de Faria Poloni, Joice, Rispoli, Thaiane, Rossetti, Maria Lucia, Trindade, Cristiano, Vargas, José Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660202/
https://www.ncbi.nlm.nih.gov/pubmed/34901273
http://dx.doi.org/10.1155/2021/5262000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660202/
https://www.ncbi.nlm.nih.gov/pubmed/34901273
http://dx.doi.org/10.1155/2021/5262000

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