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PPARα agonist relieves spinal cord injury in rats by activating Nrf2/HO-1 via the Raf-1/MEK/ERK pathway

Objective: To observe the inhibitory effects of the peroxisome proliferator-activated receptor alpha (PPARα) agonist palmitoylethanolamide (PEA) on inflammatory responses and oxidative stress injury in rats with spinal cord injury (SCI). Methods: The SCI rat model was established using modified Alle...

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Detalles Bibliográficos
Autores principales: Zhang, Haocong, Xiang, Dulei, Liu, Xinwei, Xiang, Liangbi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660597/
https://www.ncbi.nlm.nih.gov/pubmed/34799468
http://dx.doi.org/10.18632/aging.203699