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Increased proliferation and differentiation capacity of placenta-derived mesenchymal stem cells from women of median maternal age correlates with telomere shortening

Mesenchymal stem cells (MSCs) experience functional decline with systemic aging, resulting in reduced proliferation, increased senescence, and lower differentiation potential. The placenta represents a valuable source of MSCs, but the possible effect of donor age on the properties of placenta-derive...

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Detalles Bibliográficos
Autores principales: Guerrero, Erika N., Vega, Shantal, Fu, Cindy, De León, Ruth, Beltran, Davis, Solis, Mairim Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660609/
https://www.ncbi.nlm.nih.gov/pubmed/34845112
http://dx.doi.org/10.18632/aging.203724