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Increased proliferation and differentiation capacity of placenta-derived mesenchymal stem cells from women of median maternal age correlates with telomere shortening
Mesenchymal stem cells (MSCs) experience functional decline with systemic aging, resulting in reduced proliferation, increased senescence, and lower differentiation potential. The placenta represents a valuable source of MSCs, but the possible effect of donor age on the properties of placenta-derive...
Autores principales: | Guerrero, Erika N., Vega, Shantal, Fu, Cindy, De León, Ruth, Beltran, Davis, Solis, Mairim Alexandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660609/ https://www.ncbi.nlm.nih.gov/pubmed/34845112 http://dx.doi.org/10.18632/aging.203724 |
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