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Bone morphogenetic protein 9 enhances osteogenic and angiogenic responses of human amniotic mesenchymal stem cells cocultured with umbilical vein endothelial cells through the PI3K/AKT/m-TOR signaling pathway

Background: Neovascularization plays an essential part in bone fracture and defect healing, constructing tissue engineered bone that targets bone regeneration. Bone morphogenetic protein 9 (BMP9) is a regular indicator that potentiates osteogenic and angiogenic differentiation of MSCs. Objectives: T...

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Detalles Bibliográficos
Autores principales: Liu, Ziming, Li, Yuwan, Yang, Jianye, Huang, Jiaxing, Luo, Changqi, Zhang, Jun, Yan, Wenqiang, Ao, Yingfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660623/
https://www.ncbi.nlm.nih.gov/pubmed/34837694
http://dx.doi.org/10.18632/aging.203718