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Cre-Activation in ErbB4-Positive Neurons of Floxed Grin1/NMDA Receptor Mice Is Not Associated With Major Behavioral Impairment

Extensive evidence suggests a dysfunction of the glutamate NMDA receptor (NMDAR) in schizophrenia, a severe psychiatric disorder with putative early neurodevelopmental origins, but clinical onset mainly during late adolescence. On the other hand, pharmacological models using NMDAR antagonists and th...

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Detalles Bibliográficos
Autores principales: Mallien, Anne S., Pfeiffer, Natascha, Vogt, Miriam A., Chourbaji, Sabine, Sprengel, Rolf, Gass, Peter, Inta, Dragos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660629/
https://www.ncbi.nlm.nih.gov/pubmed/34899420
http://dx.doi.org/10.3389/fpsyt.2021.750106