TTPAL promotes gastric tumorigenesis by directly targeting NNMT to activate PI3K/AKT signaling

Copy number alterations are crucial for gastric cancer (GC) development. In this study, Tocopherol alpha transfer protein-like (TTPAL) was identified to be highly amplified in our primary GC cohort (30/86). Multivariate analysis showed that high TTPAL expression was correlated with the poor prognosi...

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Detalles Bibliográficos
Autores principales: Liu, Wenxiu, Gou, Hongyan, Wang, Xiaohong, Li, Xiaoming, Hu, Xiaoxu, Su, Hao, Li, Shengmian, Yu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660633/
https://www.ncbi.nlm.nih.gov/pubmed/34642500
http://dx.doi.org/10.1038/s41388-021-01838-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660633/
https://www.ncbi.nlm.nih.gov/pubmed/34642500
http://dx.doi.org/10.1038/s41388-021-01838-x

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