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Structure of the human SAGA coactivator complex

The SAGA complex is a regulatory hub involved in gene regulation, chromatin modification, DNA damage repair and signaling. While structures of yeast SAGA (ySAGA) have been reported, there are noteworthy functional and compositional differences for this complex in metazoans. Here we present the cryog...

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Detalles Bibliográficos
Autores principales: Herbst, Dominik A., Esbin, Meagan N., Louder, Robert K., Dugast-Darzacq, Claire, Dailey, Gina M., Fang, Qianglin, Darzacq, Xavier, Tjian, Robert, Nogales, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660637/
https://www.ncbi.nlm.nih.gov/pubmed/34811519
http://dx.doi.org/10.1038/s41594-021-00682-7