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Mechanistic models of blood cell fate decisions in the era of single-cell data

Billions of functionally distinct blood cells emerge from a pool of hematopoietic stem cells in our bodies every day. This progressive differentiation process is hierarchically structured and remarkably robust. We provide an introductory review to mathematical approaches addressing the functional as...

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Detalles Bibliográficos
Autores principales: Glauche, Ingmar, Marr, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660645/
https://www.ncbi.nlm.nih.gov/pubmed/34950807
http://dx.doi.org/10.1016/j.coisb.2021.100355