Cargando…
Mechanistic models of blood cell fate decisions in the era of single-cell data
Billions of functionally distinct blood cells emerge from a pool of hematopoietic stem cells in our bodies every day. This progressive differentiation process is hierarchically structured and remarkably robust. We provide an introductory review to mathematical approaches addressing the functional as...
Autores principales: | Glauche, Ingmar, Marr, Carsten |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660645/ https://www.ncbi.nlm.nih.gov/pubmed/34950807 http://dx.doi.org/10.1016/j.coisb.2021.100355 |
Ejemplares similares
-
Revealing Dynamic Mechanisms of Cell Fate Decisions From Single-Cell Transcriptomic Data
por: Zhang, Jiajun, et al.
Publicado: (2019) -
Nanog Variability and Pluripotency Regulation of Embryonic Stem Cells - Insights from a Mathematical Model Analysis
por: Glauche, Ingmar, et al.
Publicado: (2010) -
Transcriptional Regulation of Lineage Commitment - A Stochastic Model of Cell Fate Decisions
por: Teles, Jose, et al.
Publicado: (2013) -
Optogenetic clustering of CNK1 reveals mechanistic insights in RAF and AKT signalling controlling cell fate decisions
por: Fischer, Adrian, et al.
Publicado: (2016) -
Oxygen and Cell Fate Decisions
por: Lin, Qun, et al.
Publicado: (2008)