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The OM-85 bacterial lysate inhibits SARS-CoV-2 infection of epithelial cells by downregulating SARS-CoV-2 receptor expression

BACKGROUND: Treatments for coronavirus disease 2019, which is caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), are urgently needed but remain limited. SARS-CoV-2 infects cells through interactions of its spike (S) protein with angiotensin-converting enzyme 2 (ACE2) and transme...

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Detalles Bibliográficos
Autores principales: Pivniouk, Vadim, Pivniouk, Oksana, DeVries, Avery, Uhrlaub, Jennifer L., Michael, Ashley, Pivniouk, Denis, VanLinden, Sydney R., Conway, Michelle Y., Hahn, Seongmin, Malone, Sean P., Ezeh, Peace, Churko, Jared M., Anderson, Dayna, Kraft, Monica, Nikolich-Zugich, Janko, Vercelli, Donata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660661/
https://www.ncbi.nlm.nih.gov/pubmed/34902435
http://dx.doi.org/10.1016/j.jaci.2021.11.019