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SMAC Mimetics as Therapeutic Agents in HIV Infection

Although combination antiretroviral therapy is extremely effective in lowering HIV RNA to undetectable levels in the blood, HIV persists in latently infected CD4(+) T-cells and persistently infected macrophages. In latently/persistently infected cells, HIV proteins have shown to affect the expressio...

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Detalles Bibliográficos
Autores principales: Molyer, Bengisu, Kumar, Ashok, Angel, Jonathan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660680/
https://www.ncbi.nlm.nih.gov/pubmed/34899741
http://dx.doi.org/10.3389/fimmu.2021.780400