Accurate detection of circulating tumor DNA using nanopore consensus sequencing

Levels of circulating tumor DNA (ctDNA) in liquid biopsies may serve as a sensitive biomarker for real-time, minimally-invasive tumor diagnostics and monitoring. However, detecting ctDNA is challenging, as much fewer than 5% of the cell-free DNA in the blood typically originates from the tumor. To d...

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Detalles Bibliográficos
Autores principales: Marcozzi, Alessio, Jager, Myrthe, Elferink, Martin, Straver, Roy, van Ginkel, Joost H., Peltenburg, Boris, Chen, Li-Ting, Renkens, Ivo, van Kuik, Joyce, Terhaard, Chris, de Bree, Remco, Devriese, Lot A., Willems, Stefan M., Kloosterman, Wigard P., de Ridder, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660781/
https://www.ncbi.nlm.nih.gov/pubmed/34887408
http://dx.doi.org/10.1038/s41525-021-00272-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660781/
https://www.ncbi.nlm.nih.gov/pubmed/34887408
http://dx.doi.org/10.1038/s41525-021-00272-y

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