Cargando…

Accurate detection of circulating tumor DNA using nanopore consensus sequencing

Levels of circulating tumor DNA (ctDNA) in liquid biopsies may serve as a sensitive biomarker for real-time, minimally-invasive tumor diagnostics and monitoring. However, detecting ctDNA is challenging, as much fewer than 5% of the cell-free DNA in the blood typically originates from the tumor. To d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marcozzi, Alessio, Jager, Myrthe, Elferink, Martin, Straver, Roy, van Ginkel, Joost H., Peltenburg, Boris, Chen, Li-Ting, Renkens, Ivo, van Kuik, Joyce, Terhaard, Chris, de Bree, Remco, Devriese, Lot A., Willems, Stefan M., Kloosterman, Wigard P., de Ridder, Jeroen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660781/ https://www.ncbi.nlm.nih.gov/pubmed/34887408 http://dx.doi.org/10.1038/s41525-021-00272-y

Ejemplares similares

Author Correction: Accurate detection of circulating tumor DNA using nanopore consensus sequencing
por: Marcozzi, Alessio, et al.
Publicado: (2023)

From squiggle to basepair: computational approaches for improving nanopore sequencing read accuracy
por: Rang, Franka J., et al.
Publicado: (2018)

Mapping and phasing of structural variation in patient genomes using nanopore sequencing
por: Cretu Stancu, Mircea, et al.
Publicado: (2017)

Partner independent fusion gene detection by multiplexed CRISPR-Cas9 enrichment and long read nanopore sequencing
por: Stangl, Christina, et al.
Publicado: (2020)

Patterns, Predictors, and Prognostic Value of Skeletal Muscle Mass Loss in Patients with Locally Advanced Head and Neck Cancer Undergoing Cisplatin-Based Chemoradiotherapy
por: Chargi, Najiba, et al.
Publicado: (2021)

Optimizing Nanopore sequencing-based detection of structural variants enables individualized circulating tumor DNA-based disease monitoring in cancer patients
por: Valle-Inclan, Jose Espejo, et al.
Publicado: (2021)

First experiences with (177)Lu-PSMA-617 therapy for recurrent or metastatic salivary gland cancer
por: Klein Nulent, Thomas J. W., et al.
Publicado: (2021)

Droplet digital PCR for detection and quantification of circulating tumor DNA in plasma of head and neck cancer patients
por: van Ginkel, Joost H., et al.
Publicado: (2017)

Targeted sequencing reveals TP53 as a potential diagnostic biomarker in the post-treatment surveillance of head and neck cancer
por: van Ginkel, Joost H., et al.
Publicado: (2016)

Genomic DNA Pooling Strategy for Next-Generation Sequencing-Based Rare Variant Discovery in Abdominal Aortic Aneurysm Regions of Interest—Challenges and Limitations
por: Harakalova, Magdalena, et al.
Publicado: (2011)

The Predictive Value of Low Skeletal Muscle Mass Assessed on Cross-Sectional Imaging for Anti-Cancer Drug Toxicity: A Systematic Review and Meta-Analysis
por: Huiskamp, Laura F. J., et al.
Publicado: (2020)

The association of pretreatment low skeletal muscle mass with chemotherapy dose‐limiting toxicity in patients with head and neck cancer undergoing primary chemoradiotherapy with high‐dose cisplatin
por: Bril, Sandra I., et al.
Publicado: (2021)

Pretreatment ADC is not a prognostic factor for local recurrences in head and neck squamous cell carcinoma when clinical T-stage is known
por: Peltenburg, Boris, et al.
Publicado: (2019)

Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer
por: Kloosterman, Wigard P, et al.
Publicado: (2011)

Preanalytical blood sample workup for cell‐free DNA analysis using Droplet Digital PCR for future molecular cancer diagnostics
por: van Ginkel, Joost H., et al.
Publicado: (2017)

The prognostic role of tumor infiltrating T-lymphocytes in squamous cell carcinoma of the head and neck: A systematic review and meta-analysis
por: de Ruiter, Emma J., et al.
Publicado: (2017)

The prognostic role of NK cells and their ligands in squamous cell carcinoma of the head and neck: a systematic review and meta-analysis
por: Bisheshar, Sangeeta K., et al.
Publicado: (2020)

Micronuclei-based model system reveals functional consequences of chromothripsis in human cells
por: Kneissig, Maja, et al.
Publicado: (2019)

sv-callers: a highly portable parallel workflow for structural variant detection in whole-genome sequence data
por: Kuzniar, Arnold, et al.
Publicado: (2020)

Deciphering the pathogenic consequences of chromosomal aberrations in human genetic disease
por: Kloosterman, Wigard P, et al.
Publicado: (2014)

Cancer Type Classification in Liquid Biopsies Based on Sparse Mutational Profiles Enabled through Data Augmentation and Integration
por: Danyi, Alexandra, et al.
Publicado: (2021)

Digital pathology-aided assessment of tumor-infiltrating T lymphocytes in advanced stage, HPV-negative head and neck tumors
por: de Ruiter, Emma J., et al.
Publicado: (2020)

Same-day genomic and epigenomic diagnosis of brain tumors using real-time nanopore sequencing
por: Euskirchen, Philipp, et al.
Publicado: (2017)

Low dose cisplatin weekly versus high dose cisplatin every three weeks in primary chemoradiotherapy in head and neck cancer patients with low skeletal muscle mass: The CISLOW-study protocol
por: Schaeffers, Anouk W. M. A., et al.
Publicado: (2023)

Diagnostic and Treatment-Related Challenges in Sinonasal Teratocarcinosarcoma: A Report of Three Cases
por: Scheurleer, W. F. Julius, et al.
Publicado: (2023)

Target Definition in MR-Guided Adaptive Radiotherapy for Head and Neck Cancer
por: de Ridder, Mischa, et al.
Publicado: (2022)

Genome-wide patterns and properties of de novo mutations in humans
por: Francioli, Laurent C., et al.
Publicado: (2015)

A multi-platform reference for somatic structural variation detection
por: Espejo Valle-Inclan, Jose, et al.
Publicado: (2022)

Interobserver Variability in Chest CT and Whole Body FDG-PET Screening for Distant Metastases in Head and Neck Cancer Patients
por: Senft, Asaf, et al.
Publicado: (2010)

Development of a Personalized Tumor Neoantigen Based Vaccine Formulation (FRAME-001) for Use in a Phase II Trial for the Treatment of Advanced Non-Small Cell Lung Cancer
por: Oosting, Linette T., et al.
Publicado: (2022)

Comprehensive benchmark and architectural analysis of deep learning models for nanopore sequencing basecalling
por: Pagès-Gallego, Marc, et al.
Publicado: (2023)

Substrate requirements for let-7 function in the developing zebrafish embryo
por: Kloosterman, Wigard P., et al.
Publicado: (2016)

The association between skeletal muscle measures and chemotherapy‐induced toxicity in non‐small cell lung cancer patients
por: de Jong, Corine, et al.
Publicado: (2022)

Genomic and transcriptomic plasticity in treatment-naïve ovarian cancer
por: Hoogstraat, Marlous, et al.
Publicado: (2014)

MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system
por: Kapsimali, Marika, et al.
Publicado: (2007)

Target Volume Delineation Using Diffusion-weighted Imaging for MR-guided Radiotherapy: A Case Series of Laryngeal Cancer Validated by Pathology
por: Ligtenberg, Hans, et al.
Publicado: (2018)

Cloning and expression of new microRNAs from zebrafish
por: Kloosterman, Wigard P., et al.
Publicado: (2006)

Standardized Regression Coefficients and Newly Proposed Estimators for [Formula: see text] in Multiply Imputed Data
por: van Ginkel, Joost R.
Publicado: (2020)

(68)Ga-PSMA PET-CT Imaging of Metastatic Adenoid Cystic Carcinoma
por: de Keizer, Bart, et al.
Publicado: (2016)

Assessing the prognostic value of tumor-infiltrating CD57+ cells in advanced stage head and neck cancer using QuPath digital image analysis
por: de Ruiter, Emma J., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_cbih6lblvfo8eoddprtn72s20g