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SPTBN2 regulated by miR-424-5p promotes endometrial cancer progression via CLDN4/PI3K/AKT axis

Endometrioid Endometrial Cancer (EEC) is the main subtype of endometrial cancer. In our study, we demonstrated that SPTBN2 was significantly overexpressed in EEC tissues. Upregulated SPTBN2 expression was positively associated with poor prognosis. In addition, we testified that SPTBN2 knockdown sign...

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Detalles Bibliográficos
Autores principales: Wang, Pengling, Liu, Ting, Zhao, Zhendan, Wang, Zhiling, Liu, Shujie, Yang, Xingsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660803/
https://www.ncbi.nlm.nih.gov/pubmed/34887379
http://dx.doi.org/10.1038/s41420-021-00776-7