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Cell-type-specific chromatin occupancy by the pioneer factor Zelda drives key developmental transitions in Drosophila

During Drosophila embryogenesis, the essential pioneer factor Zelda defines hundreds of cis-regulatory regions and in doing so reprograms the zygotic transcriptome. While Zelda is essential later in development, it is unclear how the ability of Zelda to define cis-regulatory regions is shaped by cel...

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Detalles Bibliográficos
Autores principales: Larson, Elizabeth D., Komori, Hideyuki, Gibson, Tyler J., Ostgaard, Cyrina M., Hamm, Danielle C., Schnell, Jack M., Lee, Cheng-Yu, Harrison, Melissa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660810/
https://www.ncbi.nlm.nih.gov/pubmed/34887421
http://dx.doi.org/10.1038/s41467-021-27506-y