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Nanoparticle-assembled bioadhesive coacervate coating with prolonged gastrointestinal retention for inflammatory bowel disease therapy

A key challenge for the effective treatment of gastrointestinal diseases including inflammatory bowel disease is to develop an orally administered drug delivery system capable of prolonged retention in the gastrointestinal tract. Herein we report a bioadhesive liquid coacervate based on hydrogen bon...

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Detalles Bibliográficos
Autores principales: Zhao, Pengchao, Xia, Xianfeng, Xu, Xiayi, Leung, Kevin Kai Chung, Rai, Aliza, Deng, Yingrui, Yang, Boguang, Lai, Huasheng, Peng, Xin, Shi, Peng, Zhang, Honglu, Chiu, Philip Wai Yan, Bian, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660811/
https://www.ncbi.nlm.nih.gov/pubmed/34887414
http://dx.doi.org/10.1038/s41467-021-27463-6