Targeting of histone methyltransferase DOT1L plays a dual role in chemosensitization of retinoblastoma cells and enhances the efficacy of chemotherapy

Aberrant and exclusive expression of chromatin regulators in retinoblastoma (RB) in contrast to terminally differentiated normal retina presents a unique opportunity of selective targeting for RB. However, precise roles of these chromatin regulators in RB development and their potential as therapeut...

Descripción completa

Detalles Bibliográficos
Autores principales: Mao, Yu, Sun, Yu, Wu, Zhixuan, Zheng, Jingzhi, Zhang, Jianing, Zeng, Jiaqi, Lee, Chunsik, Kim, Jong Kyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660841/
https://www.ncbi.nlm.nih.gov/pubmed/34887387
http://dx.doi.org/10.1038/s41419-021-04431-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660841/
https://www.ncbi.nlm.nih.gov/pubmed/34887387
http://dx.doi.org/10.1038/s41419-021-04431-y

Ejemplares similares