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Broad spectrum of CRISPR-induced edits in an embryonic lethal gene

Mendelian genetics poses practical limitations on the number of mutant genes that can be investigated simultaneously for their roles in embryonic development in the mouse. While CRISPR-based gene editing of multiple genes at once offers an attractive alternative strategy, subsequent breeding or esta...

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Detalles Bibliográficos
Autores principales: Fuselier, Kayla T. B., Salbaum, J. Michael, Kappen, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660864/
https://www.ncbi.nlm.nih.gov/pubmed/34887431
http://dx.doi.org/10.1038/s41598-021-02627-y