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Broad spectrum of CRISPR-induced edits in an embryonic lethal gene
Mendelian genetics poses practical limitations on the number of mutant genes that can be investigated simultaneously for their roles in embryonic development in the mouse. While CRISPR-based gene editing of multiple genes at once offers an attractive alternative strategy, subsequent breeding or esta...
Autores principales: | Fuselier, Kayla T. B., Salbaum, J. Michael, Kappen, Claudia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660864/ https://www.ncbi.nlm.nih.gov/pubmed/34887431 http://dx.doi.org/10.1038/s41598-021-02627-y |
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