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Sex-specific effects of aging on humoral immune responses to repeated influenza vaccination in older adults

Older adults (≥65 years of age) bear a significant burden of severe disease and mortality associated with influenza, despite relatively high annual vaccination coverage and substantial pre-existing immunity to influenza. To test the hypothesis that host factors, including age and sex, play a role in...

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Detalles Bibliográficos
Autores principales: Shapiro, Janna R., Li, Huifen, Morgan, Rosemary, Chen, Yiyin, Kuo, Helen, Ning, Xiaoxuan, Shea, Patrick, Wu, Cunjin, Merport, Katherine, Saldanha, Rayna, Liu, Suifeng, Abrams, Engle, Chen, Yan, Kelly, Denise C., Sheridan-Malone, Eileen, Wang, Lan, Zeger, Scott L., Klein, Sabra L., Leng, Sean X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660902/
https://www.ncbi.nlm.nih.gov/pubmed/34887436
http://dx.doi.org/10.1038/s41541-021-00412-6