Mitochondrial DNA leakage exacerbates odontoblast inflammation through gasdermin D-mediated pyroptosis

Alleviating odontoblast inflammation is crucial to control the progression of pulpitis. Mitochondrial DNA (mtDNA) is a vital driver of inflammation when it leaks from mitochondria of inflamed odontoblasts into the cytosol. Bacteria-induced inflammation leads to a novel type of cell death named pyrop...

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Detalles Bibliográficos
Autores principales: Zhang, Yi-Fei, Zhou, Lu, Mao, Han-Qing, Yang, Fu-Hua, Chen, Zhi, Zhang, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660913/
https://www.ncbi.nlm.nih.gov/pubmed/34887391
http://dx.doi.org/10.1038/s41420-021-00770-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660913/
https://www.ncbi.nlm.nih.gov/pubmed/34887391
http://dx.doi.org/10.1038/s41420-021-00770-z

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