Increased Energy Expenditure and Protection From Diet-Induced Obesity in Mice Lacking the cGMP-Specific Phosphodiesterase PDE9

Cyclic nucleotides cAMP and cGMP are important second messengers for the regulation of adaptive thermogenesis. Their levels are controlled not only by their synthesis, but also their degradation. Since pharmacological inhibitors of cGMP-specific phosphodiesterase 9 (PDE9) can increase cGMP-dependent...

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Detalles Bibliográficos
Autores principales: Ceddia, Ryan P., Liu, Dianxin, Shi, Fubiao, Crowder, Mark K., Mishra, Sumita, Kass, David A., Collins, Sheila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2021
Materias:
Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660992/
https://www.ncbi.nlm.nih.gov/pubmed/34620617
http://dx.doi.org/10.2337/db21-0100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660992/
https://www.ncbi.nlm.nih.gov/pubmed/34620617
http://dx.doi.org/10.2337/db21-0100

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