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Arrhythmogenic Hearts in PKD2 Mutant Mice Are Characterized by Cardiac Fibrosis, Systolic, and Diastolic Dysfunctions

Autosomal dominant polycystic kidney disease (PKD) is a hereditary disorder affecting multiple organs, including the heart. PKD has been associated with many cardiac abnormalities including the arrhythmogenic remodeling in clinical evaluations. In our current study, we hypothesized that Pkd2 gene mu...

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Detalles Bibliográficos
Autores principales: Amirrad, Farideh, Pala, Rajasekharreddy, Shamloo, Kiumars, Muntean, Brian S., Nauli, Surya M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8661014/
https://www.ncbi.nlm.nih.gov/pubmed/34901233
http://dx.doi.org/10.3389/fcvm.2021.772961